Can i test with my Clearblue fertility monitor after 5pm?

No...you have to set within 1-5 days from starting your period with first morning urine. If you get up everyday at 6 am, you can hit the on anywhere b/w 4-8 am (2 hour window on either side). It does require your first urine or your results will be skewed. you do not start it on day one of your period, you start it the following day. so, if you start on tues. you will hit start on wed when you get up. for the first 5 days you just hit the on. startting day 6 you start testing your urine. i used it twice and ended up pregnant the 1st month each time. good luck and read the directions...they are easier than they sound!